Description

Hypertension is associated with an increased risk of gout through several interconnected mechanisms. High blood pressure can affect kidney function, potentially reducing the efficiency of uric acid excretion. The relationship between hypertension and gout is bidirectional, with each condition potentially exacerbating the other. Insulin resistance, often associated with hypertension, can also impair uric acid excretion. Additionally, some medications used to treat high blood pressure, such as diuretics, can increase uric acid levels. The link between hypertension and gout may also involve shared risk factors, such as obesity and a diet high in purines and fructose. A large-scale study published in the Journal of Rheumatology found that individuals with hypertension had a significantly higher risk of developing gout compared to those with normal blood pressure [1]. Another study in the Archives of Internal Medicine demonstrated that gout was associated with a higher incidence of hypertension, suggesting a complex interplay between these conditions [2]. Managing blood pressure through lifestyle modifications and appropriate medication may help reduce the risk of gout in hypertensive individuals.