Description

Physical injury to a joint can trigger a gout attack in that area through several mechanisms. When a joint experiences trauma or injury, it can lead to local inflammation and tissue damage. This inflammatory response can cause changes in the joint environment, including alterations in pH levels and temperature, which may promote the crystallization of uric acid in the affected area. Additionally, injury can disrupt the joint's normal function and blood flow, potentially leading to reduced uric acid clearance from the joint space. The stress response to injury can also lead to hormonal changes that affect uric acid metabolism and excretion. A study published in Arthritis Care & Research found that joint trauma was associated with an increased risk of gout attacks, with the highest risk observed within 2 days of the injury [1]. Another study in the Annals of the Rheumatic Diseases suggested that even minor injuries, such as those from repetitive joint use, could increase the risk of gout attacks in susceptible individuals [2].